CV
Andrew Worthy
Summary
Currently employed at Emory University. PhD Candidate, Neuroscience Graduate Program
Education
- Ph.D in Neuroscience2028Emory University
- B.A. in Chemistry2020Emory University
Publications
- Spiteful Weapons and the Environmental Dependence of Phage2020
- Mucoidy, a general mechanism for maintaining lytic phage in populations of bacteria2020FEMS Microbiology EcologyThis study demonstrates that overproduction of exopolysaccharides, "mucoidy", allows bacterial populations to be resistant to lytic bacteriophage infection. We found that spontaneous reversion from the mucoid state to the susceptible non-mucoid state allows these phage-resistant bacterial populations to maintain lytic viruses without greatly affecting the bacterial population density.
- Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity2024eLifeThis study characterizes the various subtypes ("clades") of spinal V1 interneurons, describing their relative neurogenesis times, their distributions throughout the lumbar spinal cord, and their connections to motoneurons. It also investigates the molecular identities of further subdivisions within the Foxp2-V1 clade, and demonstrates that some of these Foxp2-V1s have connectivity that resembles reciprocal Ia inhibitory interneurons (IaINs).
- Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex2026bioRxiv (preprint)This study uses optogenetics with a fast channelrhodopsin variant (CatCh) to reveal how temporal patterns and synchrony of activity within Aβ low threshold mechanoreceptor subtypes control signal propagation to primary somatosensory cortex. We found that sustained cortical responses require synchronous activation of multiple Aβ SAI-LTMRs, while Aβ RAI-LTMRs drive robust cortical responses even with asynchronous activation.
Presentations
- V1 Interneurons Expressing Foxp2 are a Highly Heterogeneous Clade2022The Seminars in Integrative Neuroscience (SIN), Emory Cell BiologyAtlanta, GA, USAPresented research findings on the heterogeneity of spinal V1 interneurons expressing the transcription factor Foxp2.
- Renshaw Cell Modulation of Reciprocal Inhibition and Motor Output2026SOM: Cell Biology Research in ProgressAtlanta, GA, USAPresented ongoing research investigating how Renshaw cells modulate reciprocal inhibition pathways and influence motor output.
Teaching
- NBB 301: Neuroscience Laboratory2024Emory University, Department of Cell BiologyRole: Teaching AssistantAssisted with undergraduate neuroscience laboratory course, guiding students through experimental techniques and data analysis.
Portfolio
- Portfolio item number 1
